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The magnitude of individual lipid and lipoproteinresponses may be influenced by the severity and type of underlyinglipid abnormality.68 In a dose-escalation study, ER formulationof niacin with monthly 500 mg increases in dose, there wereincremental changes in LDL, HDL, and triglycerides in the doserange of 0.5–2 g daily69 (Table 10). (1996) Visualhallucinations associated with Parkinson’s disease

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Wherethe groove ofone cell faces a groove ofthe adjacent cell, a small canal-likestructure, the canaliculus (C), is formed.

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The aromatic aminesundergo metabolism mainly by cytochrome P450-mediatedreactions, yielding metabolites that form adducts with DNA(Figure 15.8).

Atmagni?ed view ( b), a fragment of one end of the metallic stent is abnor-mally located in the mid- abdomen ( black arrowheads).

aureus release potent cytotoxins, areinternalized by osteoblasts causing apoptosis, or evade the immune response by survivingand multiplying in the intracellular milieu. This phosphorylation impairs the nuclear export and degra-dation of p53 [131]. The fact that they are time-locked to an artifi-cial stimulus allows them to be averaged over hundreds of trials, dramatically boosting theirSNR even in electronically noisy ICU environments (7)

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